EURECA-m Registry Update

As we have already stated in the previous newsletter, at the EURECA-m/LUST meeting held during the ERA-EDTA Congress in London, we presented some preliminary and exploratory analyses of ABPM measurements collected in a single Centre belonging to the EURECA-m working group (Reggio Calabria). These analyses were aimed at assessing the agreement between the diagnosis of hypertension based on Pre-dialysis Blood Pressure (BP), Home BP values and 44h ABPM (which is considered the golden standard for BP measurement).
Briefly, these preliminary results indicated that Pre-dialysis BP is rather inaccurate for the diagnosis of hypertension in dialysis patients. Indeed, these results from Reggio Calabria are in keeping with Agarwal’s previously published data in the Afro-American haemodialysis population in Indianapolis (USA).

The discussion of these data at the ERA-EDTA meeting in London,  brought about an agreement among centres to start with a new project and to share efforts to confirm in the European haemodialysis patients, what had already been documented in Agarwal’s previous study . In our new project, we first want to address the feasibility of the procedure itself in a sizeable cohort of European dialysis patients. For this reason, at the meeting we invited everyone with an interest in Cardiovascular and Renal Medicine to join this new project under the umbrella of the EURECA-m working group. Since then a preliminary protocol has been circulating among many European dialysis centres. The project has two major aims:
1) to confirm in a large unselected HD population in Europe, the findings previously described in a series of Afro-American dialysis patients;
2) to test ABPM feasibility and tolerability in HD patients and in a well-matched group of essential hypertensives.

This is a very intriguing project which will hopefully be followed by several corollary studies.
So far, 25 European centres (see the following list on the left) accepted with great enthusiasm to join the project. To this aim, several Skype meetings (see the second list on the right) took place in order to discuss the main issues of the study protocol and more Skype meetings were scheduled for the near future. The final version of the study protocol is almost completed and ready to be submitted to the Ethical Committee of the coordinating centre in Reggio Calabria, Italy. All centres seem highly enthusiastic to start and their number is so huge that it is very likely we will be able to enrol something like 1000 patients, which will be the largest collection of 48 ABPM in haemodialysis patients ever recorded in Europe.

List of European centres interested in the project

Colleferro, Roma - Italy

Roma - Italy

Monza - Italy

Roma, Ostia Lido - Italy

Viareggio - Italy

Bari - Italy

S. Giovanni Rotondo - Italy

Como - Italy

Napoli - Italy

Foggia -  Italy

Palermo - Italy

Lecce - Italy

Maribor - Slovenia

Thessalonika – Greece*

Ioannina - Greece

Genova - Italy

Avellino - Italy

Firenze - Italy

Salerno - Italy

Nola - Italy

Buenos Aires - Argentina

Cosenza - Italy

Istanbul - Turkey

List of centres already contacted by Skype

Colleferro, Roma - Italy

Roma - Italy

Monza - Italy

Roma, Ostia Lido - Italy

Viareggio - Italy

Bari - Italy

S. Giovanni Rotondo - Italy

Como - Italy

Napoli - Italy

Foggia - Italy

Palermo - Italy

Lecce - Italy

Maribor - Slovenia

Thessalonika – Greece*

Ioannina - Greece

Cosenza - Italy

*The interested centres in Thessalonika are 3