ERA-EDTA Operative Headquarters
Via XXIV Maggio 38
43123 Parma – Italy
Phone: +39 0521 989078
Fax: +39 0521 959242
E-mail: secretariat@era-edta.org
ERA-EDTA Registered Office
c/o PKF Littlejohn, 15 Westferry Circus, Canary Wharf
London E14 4HD – United Kingdom
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Results from the 2012-18 DOPPS in the Gulf Cooperation Council countries now available
News, News-HomeThe newest results from the prospective cohort Dialysis Outcomes and Practice Patterns Study (DOPPS) in the Gulf Cooperation Council (GCC) describe Kt/V achievement, its predictors and its relationship with mortality. The analysis included 1544 patients aged ≥18 years dialyzed for at least 180 days in Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab […]
What should a nephrologist know about surgical assessment of potential renal transplant recipients?
News, News-HomePre-emptive transplantation is the optimum renal replacement therapy in terms of increasing life expectancy, improving quality of life and achieving the highest cost-effectiveness. Planning for the procedure requires an understanding of the following technical preconditions for successful transplant surgery: arterial and venous factors, urinary drainage, organ and recipient factors. Vasculature should be carefully evaluated in […]
Clinical considerations and strategies for treating hypertension in CKD patients
News, News-HomeHypertension is both a major cause and consequence of chronic kidney disease (CKD). It is associated with increased risk of cardiac events, stroke and kidney disease progression. The latest National Kidney Foundation Clinical Practice Guidelines recommend a blood pressure goal of <130mmHg systolic and <80mmHg diastolic for all CKD patients, regardless of the level of […]
Vitamin K supplementation protects kidneys and heart
News, News-HomeVitamin K naturally occurs as type 1, which predominantly activates hepatic, i.e. coagulation-relevant vitamin K-dependent proteins (VKDPs), and type 2, activating the extra-hepatic VKDPs, including the Matrix gla protein (MGP) and osteocalcin. The latter VKDPs seem to be involved in the prevention of ectopic mineralization, thus contributing to cardiovascular disease prevention. Patients with chronic kidney […]
The EQUAL study reports an association between kidney function decline and symptom development
News, News-HomePatients with advanced chronic kidney disease (CKD) suffer from a wide range of symptoms influencing their quality of life, morbidity and mortality rates. In order to provide better insight into the association between kidney function decline and symptom development in elderly patients with advanced CKD (eGFR ≤20mL/min/1.73m2) a prospective European Quality study on treatment in […]
Plasma exchange in the pediatric population
News, News-HomeTherapeutic plasma exchange (TPE) is performed in a wide range of hematologic, neurologic, rheumatologic, renal and conditions related to organ transplantation. However, indications and outcomes are still mostly based on adult studies and evidence-based data are still lacking for the pediatric population which can also benefit from this procedure in specific circumstances. Research by Guntulu […]
New hope for patients with primary hyperoxaluria type 1
News, News-HomeLumasiran is an investigational RNAi therapeutic that inhibits oxalate production by targeting hydroxyacid oxidase 1, which depletes glycolate oxidase. The latest results from the phase 3 ILLUMINATE-A trial suggest that lumasiran effectively reduces urinary oxalate excretion at 6 months in patients with type 1 primary hyperoxaluria. Furthermore, it was well tolerated and was not associated […]
Valsartan combined with vitamin D more efficiently reduces moderate proteinuria in IgA nephropathy
News, News-HomeIgA nephropathy is a leading causes of chronic renal disease and end stage renal disease (ESRD). The risk of progression to ESRD is associated with the level of proteinuria, thus underlining the importance of adequate proteinuria control. A prospective, single-center, randomized controlled study followed patients with IgA nephropathy and moderate proteinuria of 1.0–3.0 g/24 h receiving valsartan, […]
Results from the PDOPPS on peritoneal dialysis related infection are available
News, News-HomePeritonitis is still a major concern for peritoneal dialysis (PD) patients and caregivers. The latest Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) reports the results from an observational prospective cohort investigation of 7,051 adult PD patients from seven countries. The crude peritonitis rate was 0.28 episodes per patient-year, ranging from 0.26 in the United […]
A new approach to the treatment of uremic itch
News, News-HomeUremic pruritus remains an important issue in haemodiaysis patients. It has a high prevalence and is often associated with poor sleep quality, psychological disturbances, risk of infections and even death. Several interventions have been attempted with limited success thus far. Difelikefalin, a peripherally restricted and selective agonist of kappa opioid receptors might be a promising […]