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NDT-Educational Newsletter

Issue 18 - February 2020

EDITOR IN CHIEF: Davide Bolignano

EDITORIAL BOARD: click here for the complete list

NEWSLETTER DESIGN: Francesca Trebelli

Summary Reports from 56^th ERA-EDTA Congress

Bariatric surgery: untangling the links between diabetes, hypertension and kidney disease?

Presented by Anna Solini

Bariatric surgery (BS) in obese patients with preserved kidney function lowers the risks of estimated glomerular filtration rate (eGFR) decline, of doubling of serum creatinine and of end-stage renal disease. Since there are changes in plasma creatinine (pCr) after large weight loss, pCr-based eGFR calculating formulas, Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), tend to overestimate the correction of eGFR with regard to true measurement. Although CKD-EPI may be the best performance formula for measuring eGFR in morbidly obese, cystatin C-based eGFR (eGFRcys) would be better equation if adjusted for body surface area. BS can reduce albuminuria in patients with severe obesity and normal kidney function by reducing systemic inflammation, as high-sensitivity C-reactive protein was found as an independent risk factor for albumin to creatinine ratio (ACR).

Congress Presentation

This talk has been presented by Anna solini during the 56^th ERA-EDTA Congress in Budapest, Hungary.

View it here

Vascular access : the Achilles tendon in HHD ?

Presented by Sandip Mitra

Home haemodialysis (HHD) has been available as a modality of renal replacement therapy, since the beginning of the era of maintenance haemodialysis, for nearly six decades. The interest in this type of treatment has increased in the past few years because of its proven psychosocial benefits and notable flexibility, offering patients more freedom to pursue their work and lifestyle schedule in the convenience of their homes alongwith improved outcomes and quality of life. There has been a remarkable resurgence in the past decade in a number of countries, specifically in the interest in more frequent or intensive home hemodialysis.

Congress Presentation

This talk has been presented by Sandip Mitra during the 56^th ERA-EDTA Congress in Budapest, Hungary.

View it here

References

Read this selection of articles about the two summary report fields.

Read the articles

ERA-EDTA Twitter Dialogues

A hot off the press meta-analysis in JACC about oral anticoagulation for long term dialysis patients with non-valvular atrial fibrillation.Apixaban 5mg twice daily lowered mortality risk vs warfarin or no anticoagulation as well as bleeding risk vs other NOACs and warfarin. Is it time to change our practice?

By Evangelia Ntounousi

Comment on Twitter!

A 28 yo caucasian woman in her 3rd pregnancy, 13 weeks gestation, was referred to nephrology for gross hematúria and worsening kidney function. She has a past history of surgically corrected congenital cardiomyopathy and chronic sinusitis. On admission Screat was 2.18 mg/dl and urinary sediment revealed dysmorphic erythrocytes, non-nephrotic hematúria and leucocyturia. What exams would you ask to solve this case?

By Ana Carina Ferreira

Comment on Twitter!

Omics technologies have revolutionized kidney research and much can be done to identify non-invasive biomarkers with these approaches. Metabolomics has seen alternate fortune but has great potential as evidence accumulates. Which fluid would you use as source for Metabolomics biomarkers discovery and in which pathological setting do you think the most urgent need is?

By Francesco Pesce

Comment on Twitter!

Suggest a new ERA-EDTA Dialogue!

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