The task of the second QUEST Convention in Istanbul was to assign priority (numbers) to each parameter and to prepare a list of properties of parameters to be collected. The priority list of data of calcium and phosphate is: 1) calcium (total), 2) phosphate, 3) PTH, 4) phosphate binders, 5) active vitamin D analogs, 6) calcimimetics, 7) albumin, 8) dialysate calcium, 9) parathyroidectomy, 10) hospitalisations, 11) height, 12) dry weight, 13) bone fractures, 14) calcifications, 15) aluminum.
In Vienna, additional data for paediatric patients were added to the priority list of parameters. These were pubertal status, bone mineral density and growth hormone therapy.
The ESBONET Study: European Study of Bone and Mineral Metabolic Disorders in Renal Transplantation has been proposed by Jorge Cannata-Andia. The aim is to survey bone and mineral disorders after renal transplantation in Europe. There was a lot of discussion about this European multicenter, open, observational, prospective cohort study. About 3500 incident renal transplant patients with a functional graft, at 3 months after transplantation, will be included. The duration of the study will be 5 years. Patient data will be recorded every 3 or 6 months and gathered in the data base of the ERA-EDTA Registry.
Parameters of this study are: demographic data, medical history, life style, weight and height, creatinine, GFR, calcium, phosphate, PTH, 25(OH) and 1,25(OH)2D, albumin, glucose, haemoglobin and lipids, DEXA, fractures, bone status, hospitalizations, mortality, diabetes, blood pressure, transplant rejections and treatment with steroids, immunosuppressive drugs, calcium, diphosphonates and statins.
| Dimitrios Memmos |
| on behalf of the QUEST Calcium-Phosphate-Bone Working Group |