EURECA-m e-Newsletter
Year 4 Issue 2 May 2013
In this issue:
 
 
 
EURECA-m activities at the ERA-EDTA Istanbul Congress
 
 
 
EURECA-m Board Members
Gérard Michel London (EURECA-m Chairman)
Alberto Ortiz Arduan (EURECA-m Secretary)
David Goldsmith, UK (Editor in Chief of EURECA-m Newsletter)
Raymond Vanholder, Belgium
Patrick Rossignol, France
Adrian Covic, Romania
Mehmet Kanbay, Turkey
Danilo Fliser, Germany
Andrzej Wiecek, Poland (liaison with National Societies of Nephrology)
Ziad A. Massy, France
 
EURECA-m Advisor and LUST Study Coordinator
Carmine Zoccali, Italy
       

EURECA-m Registry Clinical Coordinator
Francesca Mallamaci, Italy

    
Epidemiology and Biostatistics Consultants
Kitty J Jager, The Netherlands
Friedo W Dekker, The Netherlands
Giovanni Tripepi, Italy
Cecile Couchoud, France
 
 
 
 
 
 
 
 
Istanbul
 
EURECA-m ongoing projects
Saturday, May 18 2013 - 9:00-9:45

EURECA-m CME 1.1
Saturday, May 18 - 10:00-11:30

EURECA-m CME 1.2
Saturday, May 18 - 11:30-13:00

EURECA-m CME 1.3
Saturday, May 18 - 14:00-15:30

EURECA-m CME 1.4
Saturday, May 18 - 15:30-17:00
 

   LUST: at the trial stage

Zoccali London LUST
Carmine Zoccali
Gérard Michel London LUST Inaugural Meeting

The "LUng water by Ultra-Sound guided Treatment to prevent death and cardiovascular events in high risk end stage renal disease patients" (LUST study) is now officially opened and patients enrollment will be started in early May. As I have repeatedly illustrated in previous newsletters, this ERA-EDTA funded trial aims at testing whether a treatment policy including ultrafiltration intensification guided by the measurement of US-B lines may serve to improve clinical outcomes in hemodialysis patients.
The 25 centers selected for participation are mapped in the accompanying Figure. In the trial we have 7 French units (Paris - Manhès, Paris - Boulogne Billancourt, Strasbourg -2 units-, Nancy, Bordeaux, Sainte Foy les Lyon), 4 Italian units (Reggio Cal, Miulli, Imola and Parma), 3 Spanish (Barcelona -2 units- and Madrid), 2 German (Saarland and Hannover), Polish (Katowice and Wroclaw) and Greek (Ioannina and Kallithea) units, and 1 British (Sheffield), Israelian (Jerusalem), Romanian (Iasi), Slovenian (Maribor), Turkish (Antalya) Units.

LUST map

The kick off meeting has been successfully organized in Barcelona, Spain, on March 8-9. In this meeting the LUST network and the organizational setting, the WEB-based study database, the standardization of USB lines and echocardiography measurements as well as ancillary projects like studies on pulse wave velocity, biochemical markers of volume/left ventricular function and bio-impedance spectroscopy were presented into detail to LUST investigators. The study milestones have been delineated. In Barcelona, surveys were made among participating centers to fine-tune the study protocol. The timing of Echocardiographic studies was collegially decided and fixed to mid-week dialysis interval (arrangements can be agreed with centers that cannot comply with this timing). The participation of individual centers to ancillary studies was preliminarily agreed. The operative protocol of LUST was appropriately fine-tuned.
The safety monitoring (set up in Nancy) and the event adjudication committee were successfully established.

We perceived in Barcelona that motivation among LUST investigators is high and this is certainly a fundamental element for the progress of the same trial. We have set up a fairly good infrastructure and are confident that LUST may be completed according to the planned study schedule. In the next newsletter we will inform you about ancillary projects and the recruitment flow.

Carmine  Zoccali - LUST Study Coordinator
Gérard Michel London - EURECA-m Chair

   EURECA-m activities at the ERA-EDTA Istanbul Congress

EURECA-m ongoing projects
Saturday, May 18 2013 - 9:00-9:45

EURECA-m CME 1.1
Saturday, May 18 - 10:00-11:30

EURECA-m CME 1.2
Saturday, May 18 - 11:30-13:00

EURECA-m CME 1.3
Saturday, May 18 - 14:00-15:30

EURECA-m CME 1.4
Saturday, May 18 - 15:30-17:00
iSTANBUL
EURECA-m Website: http://www.era-edta.org/eureca-m/eureca-m.htm