CKD-MBD Newsletter
n. 9, March 2018
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EDUCATION

Report on past educational activities
The first EUROD CME meeting Role of Bone Biopsy in Clinical Practice was held in Leuven (Belgium) on January 19, 2018. The meeting, which focused on the clinical value and practical hurdles of bone biopsy, boasted the participation of 40 attendees. Clinical cases were examined and discussed during sessions and face-to-face meetings involving both participants and experts.

The Parathyroid Hormone (PTH) Day in Chronic Kidney Disease. From Bench to Bedside CME, held in Paris (France) on September 8, 2017, was a success with 90 registered attendees. Basic science aspects of PTH, diagnostic and therapeutic issues in clinical practice have been carefully touched.
Further to a call for abstracts, the three best posters from young researchers were presented.
Final Programme and presentations shown at the meeting will be soon available on www.enp-era-edta.org (accessible to ERA-EDTA members only).
A paper with the proceedings of the PTH Day CME (coordinated by Ziad Massy, Pablo Urena, Marc Vervloet and Sandro Mazzaferro) is underway and will be submitted for review to NDT.

A Special issue on “Bone in Chronic Kidney Disease” an activity of the ERA-EDTA WG on CKD-MBD, based on the presentations given at the Bone in CKD CME meeting held in Amsterdam (Netherlands) on September 23, 2016, was published in the Journal of Nephrology Volume 30, Issue 5, October 2017
Click here to access the editorial and all articles included in this special issue of the Journal of Nephrology.

Future educational activities
The 55th ERA-EDTA Congress (to be held in Copenhagen, Denmark) features a CKD-MBD educational session: “Emerging insights in CKD-MBD”.
Click here for further information

Joint EURECA-m and CKD-MBD CME meeting to be held on September 13-15, 2018 in Thessaloniki (Greece), focusing on CKD-epidemiology, prevention, progression, pathophysiology, hypertension, diabetes, vascular diseases as well as on End-stage renal diseases and dialysis.

CKD-MBD related publications in NDT and CKJ
As a contribution from ERA-EDTA communication team, we are again reporting on the most recent CKD-MBD related papers published on the ERA-EDTA journals NDT and CKJ.
Click here for more information

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RESEARCH

The EUROD Steering Committee, chaired by Prof. Pieter Evenepoel and supported with an unrestricted grant offered by AMGEN, had its second business meeting in Leuven (Belgium) on January 18, 2018. The Committee examined the practical issues (website, EC, biobank, etc.) of the registry which will hopefully start collecting data of bone biopsies from all European countries in 2018. Both historical and incident cases will be included. The main goal of the EUROD is to stress the importance of bone biopsy in CKD. Videos showing the surgical procedure will be made available for publication on the CKD-MBD website. 

Calciphylaxis registry. The Internet site (http://www.calciphylaxis.net) is now available in several languages for local uses. The Netherlands and Belgium started case recordings. A balance of recruitments is expected for the upcoming ERA-EDTA Congress.

Publications
The review paper Bone and mineral disorders in chronic kidney disease: implications for cardiovascular health and ageing in the general population [Covic A, Vervloet M, Massy ZA, Torres PU, Goldsmith D, Brandenburg V, Mazzaferro S, Evenepoel P, Bover J, Apetrii M, Cozzolino M.]was successfully submitted and published on Lancet Diabetes and Endocrinology 2017 Oct 16. pii: S2213-8587(17)30310-8. doi: 10.1016/S2213-8587(17)30310-8. [Epub ahead of print] Review.

In the pipeline….
The CKD-MBD working group is critically reviewing the recently published update in the KDIGO guideline regarding CKD-MBD. The Working Group will take the initiative to comment on this update and share its position in a commentary (coordinated by Prof. David Goldsmith).

In addition a manuscript is being prepared describing the importance of different CKD-MBD phenotypes based on the data of the EuroDOPPS.

MBD contribution to clinical endpoints in CKD. Prof. Marc Vervloet and Prof. Ziad Massy are coordinating an ongoing evaluation of data from the large EuroDOPPS registry to identify MBD phenotypes with the highest risk for clinically relevant endpoints.

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INSTITUTIONAL

The CKD-MBD Working Group boasts, as of today (February 28, 2018), 403 ordinary members.

The CKD-MBD Board met in Paris (France) on September 7, 2017 (one day prior to the PTH Day CME Course) to plan further activities. In 2017 Prof. Adrian Covic and Prof. Pieter Evenepoel ended their term as regular Board members. Two ‘original’ Board members (Prof. David Goldsmith and Prof. Ziad Massy) also stepped out in accordance to the transitional norm applicable to all Working Groups starting from their fourth year of existence.
As a consequence, the Board elected three new regular Board members, Prof. Mariano Rodriguez, Prof. Peter Stenvinkel and Dr. Etienne Cavalier, who will intensively contribute to the dissemination of education and the promotion of research in the field of CKD-MBD in Europe. Their election was validated by the ERA-EDTA Council on October 6, 2017. Their Board membership has a duration of 3 years and will expire at the end of 2020.

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ASSOCIATION

The CKD-MBD Working Group is cooperating with the following Societies and Committees:

- The European Society of Pediatric Nephrologyy and CKD-MBD are developing common specific pathways of clinical research in the field of CKD-MBD, spanning both pediatric and adult nephrology.

- The Japanese Society of Nephrology (JSN) is jointly working with the CKD-MBD on a collaborative study looking at the differences in PTH sensitivity between Japanese and European dialysis patients. Both groups presenting at one another’s meetings with the ultimate goal of sharing expertise and education.

- The European Renal Nutrition (ERN), another official Working Group of the ERA-EDTA, and CKD-MBD are combining expertise on scientific topics at the boundaries of MBD and the nutritional impact on that.

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55th ERA-EDTA Congress
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